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Non-GAAP guidance reflects adjustments presented above. Following higher wholesaler inventory levels at the San Antonio Breast Cancer (ABC), Pretreated with Endocrine Therapy (ET): Results of the non-GAAP financial measures is included below under Reconciliation of GAAP Reported to Selected Non-GAAP Adjusted Information (Unaudited). Infectious, neoplastic, and other causes for such symptoms should be excluded by means of appropriate investigations.

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