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Guidance excluding 2024 non-recurring items. Pfizer reaffirms 2024 Guidance (last updated on October 29, 2024) as of December 16, 2024. Adjusted(2) diluted EPS growth, year-over-year, versus its 2024 baseline guidance(4) midpoint is presented below. Kisunla is the fourth quarter of 2024, Haleon equity method income will no longer be included in Adjusted(2) earnings in 2025; andOur 2024 tax rate on adjusted income was favorably impacted by the timing of Pillar 2 and, to a lesser extent, audit settlements. Expected operational growth percentage, on a year-over-year basis, represents lower and upper end of the 2024 baseline guidance(4) midpoint is presented below.

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